{"id":112,"date":"2023-06-20T20:19:04","date_gmt":"2023-06-20T20:19:04","guid":{"rendered":"https:\/\/dev.impact2022-static.test\/?post_type=portfolio-company&p=112"},"modified":"2023-10-10T10:58:17","modified_gmt":"2023-10-10T10:58:17","slug":"closed-loop-medicine","status":"publish","type":"portfolio-company","link":"https:\/\/dev.impact2022-static.test\/portfolio-company\/closed-loop-medicine\/","title":{"rendered":"Closed Loop Medicine"},"excerpt":{"rendered":"","protected":false},"featured_media":1121,"template":"","meta":[],"tags":[],"class_list":["post-112","portfolio-company","type-portfolio-company","status-publish","has-post-thumbnail","hentry"],"meta_box":{"portco_impact_summary_text":"Closed Loop Medicine improves patients outcomes through drug dose optimisation.","portco_impact_description_text":"

All medicines are poison. The dose alone determines if it is a poison or not. Closed Loop Medicine have clinically evidenced that dose optimisation improves outcomes for patients through using a combination of known medicines + software, enabling a personalised approach to care.<\/p>\n","portfolio_company_impact":{"filesize":172466,"ID":"1653","name":"Ananda_Closed-Loop-Medicine_Precision-medicine-1.svg","path":"\/Users\/christopherverbick\/Sites\/dev.impact2022-static\/wp-content\/uploads\/Ananda_Closed-Loop-Medicine_Precision-medicine-1.svg","url":"https:\/\/dev.impact2022-static.test\/wp-content\/uploads\/Ananda_Closed-Loop-Medicine_Precision-medicine-1.svg","full_url":"https:\/\/dev.impact2022-static.test\/wp-content\/uploads\/Ananda_Closed-Loop-Medicine_Precision-medicine-1.svg","title":"Ananda_Closed-Loop-Medicine_Precision-medicine-1","caption":"","description":"","alt":"","srcset":false,"width":false,"height":false},"portco_impact_order":"6","portco_impact_infographic_caption_text":"","portco_impact_infographic":{"filesize":172466,"ID":"1653","name":"Ananda_Closed-Loop-Medicine_Precision-medicine-1.svg","path":"\/Users\/christopherverbick\/Sites\/dev.impact2022-static\/wp-content\/uploads\/Ananda_Closed-Loop-Medicine_Precision-medicine-1.svg","url":"https:\/\/dev.impact2022-static.test\/wp-content\/uploads\/Ananda_Closed-Loop-Medicine_Precision-medicine-1.svg","full_url":"https:\/\/dev.impact2022-static.test\/wp-content\/uploads\/Ananda_Closed-Loop-Medicine_Precision-medicine-1.svg","title":"Ananda_Closed-Loop-Medicine_Precision-medicine-1","caption":"","description":"","alt":"","srcset":false,"width":false,"height":false},"quote_text":"Precision medicine, where healthcare treatments are tailored to the individual has, until now, only been applied to a handful of medical conditions. What if it could be applied more widely?\"","quote_name":"Dr Hakim Yadi","quote_role":"CEO","quote_company_name":"Closed Loop Medicine","quote_article_link_text":"Read more","quote_link_to_article":"https:\/\/www.nature.com\/articles\/s41587-021-00941-4#auth-Hakim-Yadi-Aff40","quote_photo":[{"width":150,"height":150,"file":"Closed-Loop-Medicine-Hakim-Yadi.png","filesize":1101629,"sizes":{"medium":{"file":"Closed-Loop-Medicine-Hakim-Yadi-300x300.png","width":300,"height":300,"mime-type":"image\/png","filesize":86570,"url":"https:\/\/dev.impact2022-static.test\/wp-content\/uploads\/Closed-Loop-Medicine-Hakim-Yadi-300x300.png"},"large":{"file":"Closed-Loop-Medicine-Hakim-Yadi-1024x1024.png","width":1024,"height":1024,"mime-type":"image\/png","filesize":782727,"url":"https:\/\/dev.impact2022-static.test\/wp-content\/uploads\/Closed-Loop-Medicine-Hakim-Yadi-1024x1024.png"},"thumbnail":{"file":"Closed-Loop-Medicine-Hakim-Yadi-150x150.png","width":150,"height":150,"mime-type":"image\/png","filesize":25501,"url":"https:\/\/dev.impact2022-static.test\/wp-content\/uploads\/Closed-Loop-Medicine-Hakim-Yadi-150x150.png"},"medium_large":{"file":"Closed-Loop-Medicine-Hakim-Yadi-768x768.png","width":768,"height":768,"mime-type":"image\/png","filesize":475231,"url":"https:\/\/dev.impact2022-static.test\/wp-content\/uploads\/Closed-Loop-Medicine-Hakim-Yadi-768x768.png"}},"image_meta":{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0","keywords":[]},"ID":"2095","name":"Closed-Loop-Medicine-Hakim-Yadi.png","path":"\/Users\/christopherverbick\/Sites\/dev.impact2022-static\/wp-content\/uploads\/Closed-Loop-Medicine-Hakim-Yadi.png","url":"https:\/\/dev.impact2022-static.test\/wp-content\/uploads\/Closed-Loop-Medicine-Hakim-Yadi-150x150.png","full_url":"https:\/\/dev.impact2022-static.test\/wp-content\/uploads\/Closed-Loop-Medicine-Hakim-Yadi.png","title":"Hakim Yadi - Founder & CEO - Closed Loop Medicine","caption":"Dr. Hakim Yadi OBE - Distinctive figure in healthcare, CEO & Cofounder of Closed Loop Medicine, and recipient of an OBE for services to Healthcare Technology.","description":"Dr. Hakim Yadi OBE is at the forefront of innovative healthcare, boasting a rich history of managing and channeling investment into pivotal healthcare research entities. His leadership prowess was evident as the CEO of the Northern Healthcare Alliance, unifying 20 Research Hospitals. With a PhD in Immunology of Pregnancy from the University of Cambridge, Dr. Yadi's contributions to the healthcare sector were notably recognized in 2017 when he was conferred an OBE by H.M. The Queen.","alt":"Photo of Dr. Hakim Yadi OBE, CEO & Cofounder of Closed Loop Medicine, renowned for leadership in healthcare research and investment.","srcset":"https:\/\/dev.impact2022-static.test\/wp-content\/uploads\/Closed-Loop-Medicine-Hakim-Yadi-150x150.png 150w, https:\/\/dev.impact2022-static.test\/wp-content\/uploads\/Closed-Loop-Medicine-Hakim-Yadi-300x300.png 300w, https:\/\/dev.impact2022-static.test\/wp-content\/uploads\/Closed-Loop-Medicine-Hakim-Yadi-1024x1024.png 1024w, https:\/\/dev.impact2022-static.test\/wp-content\/uploads\/Closed-Loop-Medicine-Hakim-Yadi-768x768.png 768w, https:\/\/dev.impact2022-static.test\/wp-content\/uploads\/Closed-Loop-Medicine-Hakim-Yadi.png 1200w"}],"company_tagline":"Improving patient outcomes through tailored, personalised care","company_description":"Closed Loop Medicine improves drug effectiveness and patient outcomes through the development of a safe, protectable and scalable product solution that combines dose-optimized drug therapy with digital care.","why_it_matters_-_icon_1":{"filesize":2046,"ID":"1161","name":"ClosedLoopMedicine-medication-1.svg","path":"\/Users\/christopherverbick\/Sites\/dev.impact2022-static\/wp-content\/uploads\/ClosedLoopMedicine-medication-1.svg","url":"https:\/\/dev.impact2022-static.test\/wp-content\/uploads\/ClosedLoopMedicine-medication-1.svg","full_url":"https:\/\/dev.impact2022-static.test\/wp-content\/uploads\/ClosedLoopMedicine-medication-1.svg","title":"ClosedLoopMedicine-medication-1","caption":"","description":"","alt":"","srcset":false,"width":false,"height":false},"why_it_matters_-_text_1":"

Medical costs due to non-optimised medication therapy are estimated at USD 530 billion in the US annually<\/strong>.<\/p>\n","why_it_matters_-_icon_2":{"filesize":1276,"ID":"1162","name":"ClosedLoopMedicine-side-effects-2.svg","path":"\/Users\/christopherverbick\/Sites\/dev.impact2022-static\/wp-content\/uploads\/ClosedLoopMedicine-side-effects-2.svg","url":"https:\/\/dev.impact2022-static.test\/wp-content\/uploads\/ClosedLoopMedicine-side-effects-2.svg","full_url":"https:\/\/dev.impact2022-static.test\/wp-content\/uploads\/ClosedLoopMedicine-side-effects-2.svg","title":"ClosedLoopMedicine-side-effects-2","caption":"","description":"","alt":"","srcset":false,"width":false,"height":false},"why_it_matters_-_text_2":"

Too many patients, particularly those affected by chronic disease, fail to gain any benefit from taking pills and tend to suffer a number of negative side-effects<\/strong>.<\/p>\n","why_it_matters_-_icon_3":{"filesize":3540,"ID":"1160","name":"ClosedLoopMedicine-inefficiency-3.svg","path":"\/Users\/christopherverbick\/Sites\/dev.impact2022-static\/wp-content\/uploads\/ClosedLoopMedicine-inefficiency-3.svg","url":"https:\/\/dev.impact2022-static.test\/wp-content\/uploads\/ClosedLoopMedicine-inefficiency-3.svg","full_url":"https:\/\/dev.impact2022-static.test\/wp-content\/uploads\/ClosedLoopMedicine-inefficiency-3.svg","title":"ClosedLoopMedicine-inefficiency-3","caption":"","description":"","alt":"","srcset":false,"width":false,"height":false},"why_it_matters_-_text_3":"

The outcomes are suboptimal health outcomes and inefficient use of resources<\/strong> by the healthcare system.<\/p>\n","impact_kpi_subheading":"The data below shows the year-on-year change in impact KPIs for CLM (updated 2022).","impact_kpi_value_1":"+9%","impact_kpi_color_-_value_1":"#619B5D","impact_kpi_text_1":"

number of patients supported<\/strong> through fine stage clinical studies<\/p>\n","impact_kpi_value_2":"+13%","impact_kpi_color_-_value_2":"#619B5D","impact_kpi_text_2":"

number of medical conditions addressable<\/strong> by Closed Loop Medicine\u2019s personalised drug+digital 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app is like an angel on my shoulder.\u201d","stakeholder_quote_1_name_and_role":"Clinical trial 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is an important study in that it allows patients and physicians to collect real-world data to help better inform treatment decisions and monitor patient outcomes. 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